I've been using the Power Bar version for a couple of years. It basically buffers your muscles against the burn caused by the release of that hydrogen ion when the muscle contracts. Does it work? Seems to. As with anything like this its not like one day you find that you can ride way over your FTP and not notice your heart coming out of your chest but I do think there is some legit science behind it as backed up by my sports dietician and her research into it.